葡萄牙布拉加皮肤真菌病的20年调查
Valdigem G. L.[1] Pereira T.[1] Macedo C.[1] 吴佳纹(译)[2]
[1]Life and Health Sciences Research Institute, School of Health Sciences, University of Minho, 4710-057 Braga, Portugal [2]不详, School of Health Sciences, University of Minho, 4710-057 Braga, Portugal
摘 要:
背景:由于社会习性改变及移居增多,不仅增加了皮肤真菌病的发病率并且改变了其发病原因。近几年,布拉加的生活方式发生了巨变,已从乡村性转变为国际性。方法:通过对1983--2002年间来自葡萄牙布拉加de Saeo Mareos医院的患者回顾性调查,进行皮肤真菌病和其致病因素的统计学研究。在该研究中,共对10003例患者进行分析。结果:在此期间,皮肤真菌病的发病率(以培养出皮肤癣菌来确定)为23.6%,而非皮肤真菌感染者为7.0%。对临床表现及分离出的真菌分析后提示皮肤癣菌在机体有一定的好发区域(P≤0.01)。年龄是影响皮肤真菌病发生的非常重要因素(P≤0.0001),对于年龄增长与感染的相关性,结果表明红色毛癣菌相关而犬小孢子菌不相关。患者的性别并非皮肤真菌病发生的相关因素,然而发现某些病原体的分布存在显著性差异(P≤0.05)。结论:结果显示皮肤真菌病主要病原体为红色毛癣菌(37.4%)。此外布拉加的皮肤真菌病发病率正在下降并且呈现出新趋势,而且研究发现麦格尼(氏)毛癣菌的感染率已下降。[第一段]
文章出处:
《世界核心医学期刊文摘:皮肤病学分册》-2006年2卷9期 -52-53页
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相关文章:
A twenty-year survey of dermatophytoses in Braga, Portugal
Valdigem G. L.,Pereira T. , Macedo C. et al.( Life and Health Sciences Research Institute, School of Health Sciences, University of Minho, 4710-057 Braga, Portugal)
Abstract:
Background: Modifications in social habits together with the increase of emigration have contributed not only to increased dermatophytoses but also to an altered etiology. During the last few years, Braga has suffered a radical change from a rural to a cosmopolitan life-style. Methods: A statistical study of dermatophytoses and the etiology of their causative agents was performed by a retrospective survey carried out among patients of Hospital de Saeio Marcos, Braga, Portugal, from 1983-2002. In this study, a total of 10 - 003 patients were analyzed. Results: Over this period the frequency of dermatophytoses, as defined by the recovery of a dermatophyte in culture, was found to be 23.6%, whereas nondermatophytic infections accounted for 7.0%. Analysis of the clinical form s and the isolated fungi supports that the dermatophyte species have a predilection for certain body areas (P ≤ 0. 01). Age is a very important factor regarding the occurrence of dermatophytoses (P ≤ 0. 0001), with a correlation between increasing age and infection, positive for Trichophyton rubrum and negative for Microsporum canis. Overall the gender of the patients is not an association factor for the development of dermatophytoses; however, significant differences were detected in the distribution of some etiologic agents (P≤ 0. 05). Conclusions: The results showed the main etiologic agent of dermatophytoses to be Trichophyton rubrum (37.4%) . Moreover, dermatophytoses are both decreasing and showing a new profile in Braga, and a pronounced decrease of Trichophyton megninii was observed throughout the study.[第一段]

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