您的位置：网站首页 > 《中文科技期刊数据库》 > 医药卫生 > 临床医学 > 内分泌与代谢疾病 > 摘要
Nardostachys jatamansi extract protects against cytokine-induced β-cell damage and streptozotocin-induced diabetes
Mi-Young Song Ui-Jin Bae Bong-Hee Lee Kang-Beom Kwon Eun-A Seo Sung-Joo Park Min-Sun Kim Ho-Joon Song Keun-Sang Kwon Jin-Woo Park Do-Gon Ryu Byung-Hyun Park Department of Biochemistry Medical School and Diabetes Research Center Chonbuk National University Jeonju Jeonbuk 561-756 South Korea Department of Physiology School of Oriental Medicine Wonkwang University Iksan Jeonbuk 570-749 Department of Food and Nutrition School of Human Environmental Science Department of Herbology Department of Preventive Medicine Medical School| 《世界胃肠病学杂志：英文版》2010年 第26期 | 摘要：AIM: To investigate the anti-diabetogenic mechanism of Nardostachys jatamansi extract (NJE). METHODS: Mice were injected with streptozotocin viaa tail vein to induce diabetes. Rat insulinoma RINm5F cells and isolated rat islets were treated with interleukin1β and interferon-γ to induce cytotoxicity. RESULTS: Treatment of mice with streptozotocin resulted in hyperglycemia and hypoinsulinemia, which was conf irmed by immunohistochemical staining of the islets. The diabetogenic effects of streptozotocin were c... | |
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| 来源期刊：《世界胃肠病学杂志：英文版》2010年 第26期 | ||
| 收录数据库：中文科技期刊数据库 | ||
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