学术
摘 要:
目的探讨幼年特发性关节炎（JIA）的临床特点及治疗方法。方法按照国际风湿病学联盟（ILAR）新的分类标准对JIA患儿进行分型，总结37例JIA患儿的临床表现、实验室和影像学检查结果及药物治疗及其转归。结果全身型22例（59．46％），少关节型7例（18，92％），多关节型5例（1351％），其他关节炎型3例（8．10％）。全身型以非类固醇性抗炎药（NSAIDs）＋缓解病情抗风湿药物（DMARIN）＋激素治疗为主，其中8例加用细胞毒药物（CTX）；少关节型、多关节型及其他关节炎型以NSAIDs＋DMARDs＋小剂量激素治疗，基本能够控制病情，无1例发生关节功能障碍。结论JIA以全身型最多见，其次为少关节型；JIA冶疗也提倡早期联合治疗，以尽快控制炎症，改善病情，防止残疾发生。[著者文摘]
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文章出处:
《实用儿科临床杂志》-2006年21卷9期 -534-535页
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文献标识码:
A
文章编号:
1003-515X（2006）09-0534-02
Thirty- Seven Cases with Juvenile Idiopathic Arthritis
MAO Hai - ying , CAO Lan - fang, MA Min , ZHAO Yu （Department of Pediatrics, Renji Hospital Affiliated to Medical College of Shanghai Jiaotong University,Shanghai 200001, China）
Abstract:
Objective To discuss the classification, differential diagnosis, and treatment of juvenile idiopathic arthritis （JIA）. Methods The study population consisted of 37 JIA children and its subgroups as defined by the International League of Associations for Rheurnatology （ILAR） classification criteria. A clinical reevaluation was carried out. The various subtypes of JIA and their clinical features were described, together with an overview of their differential diagnosis, complications and outcomes. An outline of current management strategies was given and potential future developments highlighted. Results Twenty two cases with systemic onset course JIA （59.46%） ;5 cases with polyarticular onset（ 13.51% ）,7 case-s with oligoarticular court（ 18.92 % ）. The treatment regimens showed that 8 of 22 children with systemic onset course JIA were received CTX;all children with systemic onset course JIA were received non - steroidal anti-inflmmatory agents （NSAIDs）,disease modifying antirheumatic drugs （DMARDs） in addition to systemic corticosteroids. Patients with oligoarticular ccourse polyarticular onset and others were received NSAIDs,DMARDs in addition to low dose systemic corticosteroids,and none of them occurred severity of joint involvement. Conclusion Patients with systemic onset course JIA are most common, and secondly are oligoarticular course.The treatment of JIA should be earlier,tesing combined drugs.[著者文摘]
Key words:
arthritis, juvcnile idiopathic; diagnosis; treatment; child
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