摘 要:
新一代药物洗脱支架由可吸收多聚物为平台,具有与金属支架相当的的支撑力,以及良好的生物相容性。既可以暂时支撑管壁,抑制早期血栓形成及晚期新生内膜增生,还可作为良好的药物载体实现局部控制释放,达到有效防止支架置入后的血管急性闭塞和降低再狭窄率。[著者文摘]
文章出处:
《心血管病学进展》-2008年29卷1期 -47-49页
Advances in Cardiovascular Diseases
栏目信息:
文献标识码:
A
文章编号:
1004-3934(2008)01-0047-03
Advances in Study of Polymeric Bioabsorbable Coronary Stents
GUO Yan, QING Yong-wen (Department of Cardiology, Changhai Hospital of The Second Military Medical University, Shanghai 200433, China)
Abstract:
Bioabsorbable polymers have been used as the platform of a novel coronary stent, which has strength comparable to stainless steel stents and biocompatibility with the vessel wall. The role of stenting is temporary. Therefore early thrombosis and late neointimal proliferation are inhibited. It can also be used as an ideal delivery device for drugs, and enables local and controlled drug release strategies, and thus effectively, to prevent acute occlusion and reduce restenosis after stenting.[著者文摘]
Key words:
bioabsorbable stent;polymers ;restenosis
收稿日期: 2007-05-09
修订日期: 2007-07-19

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