摘 要:
目的调查2002-2005年湖北地区铜绿假单胞菌的耐药性及流行趋势,为临床提供诊疗依据。方法采用WHONET4,5软件对6208株铜绿假单胞菌株的耐药率进行统计分析,所有菌株分离自湖北地区17所三级医院成人患者2002-2005年的各类临床标本。结果4a中湖北地区铜绿假单胞菌对常用抗菌药物的耐药率总体持平或小幅度上升,2005年铜绿假单胞菌对碳青霉烯类药物亚胺培南和美罗培南耐药率分别为25%和23%,略低于中国CHINET细菌耐药性监测结果。结论坚持细菌耐药性的监测与公示、合理使用抗菌药物,对控制耐药茵的传播与流行具有重要意义。[著者文摘]
文章出处:
《医药导报》-2007年26卷11期 -1370-1371页
栏目信息:
分 类 号:
文献标识码:
A
文章编号:
1004-0781(2007)11-1370-02
Investigation on Changes of Drug Resistance of Pseudomonas Aeruginosa among the Third Grade Hospitals in Hubei Province
TIAN Song, PENG Shao-hua, CAI Xuan, SHI Jin-ling, SUN Duan-yang( Department of Clinical Laboratory, Renmin Hospital of Wuhan University, Wuhan 430060, China)
Abstract:
Objective To explore antibiotics resistance and epidemiology of Pseudomonas aeruginosa and to provide evidence for clinical treatment and diagnosis. Methods The ratio of antibiotics resistance in 6208 species of P. aeruginosa isolated from adult patients of 17 third grade hospitals in Hubei area since 2002 - 2005 was analyzed by using WHONET4-5 software. Results During the four years, the resistance to antibiotics in P. aeruginosa was on slight rise; the resistance to imipenem and meropenem were 25% and 23%, respectively which was lower than the results reported by CHINET antibiotic resistance investigation. Conclusion It is important to control the spread of the drug resistant bacteria by insisting on monitoring and public showing the antibiotic resistance, and rational using of antibiotics.[著者文摘]
Key words:
Pseudomonas aeruginosa; Antibiotics resistance ;The third grade hospitals
基金资助:
基金项目:湖北省卫生厅重点基金资助项目(基金编号:WJ01564)

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