学术
摘 要:
目的：了解我院结直肠围手术期抗菌药物的应用情况。方法：随机抽取我院胃肠外科2006年结直肠手术病例213例，按手术时间及手术区污染情况分为Ⅰ类手术及Ⅱ类手术2组，分别对术前、术中、术后抗菌药物应用种类及应用时间进行调查，并对术后感染情况进行分析。结果：术前预防用药均在1～3d内，用药方案较统一，多为口服氨基糖苷类及甲硝唑；术中均为单次用药，多为第3代头孢菌素类与甲硝唑联用；术后用药较复杂，Ⅰ类手术多为2药联用，用药时间多在3～7d，Ⅱ类手术多为3药联用，用药时间多在6--7d以上。术后感染Ⅰ型手术组为3．4％，Ⅱ类手术组为11．6％，两组间有显著性差异。结论：我院结直肠手术围手术期抗菌药物应用以第3代头孢菌素类＋甲硝唑为主，应用较规范，但术后用药还存在一定误区。[著者文摘]
文章出处:
《中国药房》-2007年18卷32期 -2499-2500页
栏目信息:
文献标识码:
C
文章编号:
1001-0408（2007）32-2499-02
Perioperative Use of Antibiotics in Patients Undergoing Colorectal Operations
TANG Lei,SONG Qihong, HE Xiaomin,ZHU Yifan（The First Affiliated Hospital of Sun Yat- Sen University, Guangzhou 510080, China）
Abstract:
OBJECTIVE： To investigate the perioperative use of antibiotics in patients undergoing colorectal operations. METHODS： The medical records of 213 patients undergoing colorectal operations in 2006 were randomly selected from the gastrointestinal surgery department of our hospital and divided into type Ⅰ operation group and type Ⅱ operation group according to patients＇ operation time and wound contamination .The kinds and medication duration of antibiotics used before, during and after operation were investigated, and the postoperative infections were analyzed .RESULTS： The preoperative preventive medication were all conducted within the first 1--3days, and the dosage schemes were unified with aminoglycosides and metronidazole topping the list .The antibiotics used during operation were all in single dose,with 3rd generation cephalosporins combined metronidazole predominantly used.Postoperative use of antibiotics was somewhat complicated： type Ⅰ operation patients were treated more often by 2 kinds of antibiotics concurrently for 3--Tdays and type Ⅱ operation patients were treated more often by 3 kinds of antibiotics concurrently for at least 6-7days.The incidence of postoperative infection was 3.4% in type Ⅰ operation patients as compared to 11.6% in type Ⅱ operation patients, showing significant differences between two groups.CONCLUSION： The perioperative application of antibiotics in patients undergoing colorectal operation was reasonable on the whole, with 3rd generation cephalosporins plus metronidazole predominantly used, but there were some problems in the postoperative medication.[著者文摘]
Key words:
Colorectal operation;Perioperative period;Antibiotics
更多>>免费文章
cqvip.com