学术
中国四个海拔牦牛群体血红蛋白β链微卫星多态性分析
袁青妍[1] 黄治国[1] 石绍华[1] 谢庄[1] 刘红林[1] 殷甫路[2] 赵永华[3]
[1]南京农业大学动物科技学院,江苏南京210095 [2]红松洼种畜场,河北承德310034 [3]龙日种畜场,四川红原624400
摘 要:
分析了四个海拔高度牦牛（4500m，4000m，3500m，1700m）血红蛋白β链微卫星座位的多态性，结果发现中国牦牛群体的平均杂合度和多态信息含量分别为0．8574，0．8426，等位基因数为10，其中7个是牦牛所特有的，另外3个是牦牛和黄牛所共有的。四个海拔高度牦牛的等位基因分布差异极显著（P〈0．01）。等位基因分布与海拔相关，相关系数为0．397。基因型121bp／103bp是海拔4000m处牦牛所特有的。这说明高度多态的血红蛋白β链微卫星座位在牦牛适应高原低氧中具有可能的自然选择价值及可能的调控作用。[著者文摘]
文章出处:
《家畜生态学报》-2005年26卷5期 -11-14页
栏目信息:
分 类 号:
文献标识码:
A
文章编号:
1004-5228（2005）05-0011-04
Microsatellite Polymorphism of β-globin locus （HBB） in Four Altitude Chinese Yak Populations
YUAN Qing-yan, HUANG Zhi-guo , SHI Shao-hua , XIE zhuang , LIU Hong-lin, YIN Pu-lu, ZHAO Yong-hua （1. College of Animal Science and Technology, Nanjing Agricultural University, Nanjing Jiangsu 210095, ChinK; Hongsongwa Breed Farm, Chengde Hebei 310034, China; 3. Longri Breed Farm, Hongyuan Sichuan 624400, China）
Abstract:
Studies on the microsatellite polymorphism of β-globin locus in yak at four altitudes （4500 m, 4000 m, 3500 m, 1700 m） were undertaken. The H （heterozygosity） and PIC （polymorphic information contents） of yak were 0. 8574 and 0. 8426 respectively. 10 alleles were detected in yak including 7 unique ones. The remaining three were the common alleles of yak and cattle. The allele distribution for yaks of four altitudes was significantly different （Pal0. 01）. There was a correlation between allele distribution and altitude with a correlation coefficient of 0. 397. The genotype 121bp/103bp was found to be unique to the yak living at altitude of 4000 m. The high polymorphic β-globin locus shows its possible natural selective value in the adaptation of yak to high altitude hypoxia and perhaps its possible regulatory role in the synthesis of hemoglobin.[著者文摘]
Key words:
microsatellite polymorphism ; β-globin locus ; yak
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