学术
一种新的雄甾烷衍生物的NMR数据分析
陈才法[1] 蒋虹[1] 刘新友[3] 冯友建[1] 屠树江[2] 顾菲[2] 辜顺林[2]
[1]江苏省药用植物生物技术重点实验室 徐州师范大学,江苏徐州221116 [2]徐州师范大学化学化工学院,江苏徐州221116 [3]第四军医大学唐都医院药剂科,陕西西安710038
国际标准刊号：ISSN 1000-4556
国内统一刊号：CN 42-1180
摘 要:
采用^1H NMR，^13C NMR，DEPT，^1H-^1H COSY，HSQC，HMBC等多种核磁共振分析方法，确证了溴化1-[3α，17β-二乙酰氧基-2β-（1-哌啶基）-5α-雄甾烷-16β基]-1-乙腈基哌啶的结构，对它的^1H和^13C NMR谱信号进行了归属和详细分析，为其结构鉴定提供了依据．[著者文摘]
文章出处:
《波谱学杂志》-2008年25卷1期 -80-86页
Chinese Journal of Magnetic Resonance
分 类 号:
文献标识码:
A
文章编号:
1000-4556（2008）01-0080-07
[参考文献]
Assignment of Chemical Shifts of a Novel Androstan Derivative
CHEN Cai-fa, JIANG Hong , LIU Xin-you , FENG You-jian, TU Shu-jiang , GU Fei , GU Shun-lin （1. The Key Laboratory of Biotechnology for Medicinal Plants of Jiangsu, Xuzhou Normal University, Xuzhou 221116, China; 2. College of Chemistry and Chemical Engineering, Xuzhou Normal University, Xuzhou 221116, China; 3. Department of Pharmacy of Tangdu Hospital, The Fourth Military Medical University, Xi＇an 710038, China）
Abstract:
The molecular structure of a novel androstan derivative was elucidated by 1D and 2D NMR techniques, including ^1H NMR, ^13C NMR, DEPT, ^1H-^1H COSY, HSQC and HMBC. The ^1H and ^13C chemical shifts of the compound were assigned. The structure of the compound was determined to be 1-[3α, 17β-diacetyloxy-2β（1-piperdinly）-5α- androstan- 16β-yl-]-1-acetonitrily piperdinium bromide.[著者文摘]
Key words:
NMR, assignment, 2D NMR androstan
收稿日期: 2007-04-04
修订日期: 2007-05-23
基金资助:
国家自然科学基金资助项目（20372057）;江苏省大型科学仪器设备共享服务平台理事会资助项目;徐州市科技发展基金（XJ07066）;徐州师范大学自然科学研究基金资助项目（05XLB30）.
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