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比例优势模型在多结局区间截断数据上的应用

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郑明 杜玮

复旦大学统计系,上海200433

应用数学
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国际标准刊号:ISSN 1001-9847
国内统一刊号:CN 42-1184

摘  要:

探索比例优势模型在临床医学中常见的多结局区间截断数据中的应用.用条件的逻辑回归方法避免讨厌参数的估计,用牛顿-拉普森算法估计回归系数,用"夹心方差"估计量作为参数方差的估计.通过随机模型检验模型应用的有效性.[著者文摘]

odds model;M ultivariate interval—censored;ConditionallO—gistie regression;Sandwich estimator CLC Number:O212.1;0213.9 AMS(2000)Subject Classification:62P10;62J12 Document code:A Artiele ID:1001-9847(2007)04—0726—07 1.IntrOductiOn In the real life.some clinic events of interest can not be observed as soon as they OC—eurred.Instead,the time of occurrence iS known only to fall between two successive examina—tions,one preceding a......

文章出处:

《应用数学》-2007年20卷4期 -726-732页

Mathematica Applicata

分 类 号:

O212.1 O213.9

文献标识码:

A

文章编号:

1001-9847(2007)04-0726-07

相关文章:

参考文献(10篇)  主题相关

[参考文献]

Applications of Proportional Odds Model to Multivariate Interval-Censored Data

ZHENG Ming(Department of Statistics,Fudan University,Shanghai 200433,China)  DU Wei(Department of Statistics,Fudan University,Shanghai 200433,China) 

Abstract:

Since the multiple failures situation is not uncommon in the clinical medicine,we explore the use of proportional odds model to the multivariate interval-censored data.The approach is based on the conditional logistic regression,which prevents the complications in the existence of nuisance parameters.The estimation of parameters is obtained by the Newton-Raphson algorithm.The sandwith estimator for the covariance is made according to the situation where there is correlation in the score statistic.Simulations are also presented to assess the accuracy of the procedure.[著者文摘]

Key words:

Proportional odds model;Multivariate interval-censored;Conditional logistic regression;Sandwich estimator

收稿日期: 2007-04-02

基金资助:

Supported by the National Natural Science Foundation of China(10671038)

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