This companion title to the highly-regarded Journal of Infection, provides a forum for the advancement of knowledge and discussion of clinical infection in practice. It embraces relevant clinical research and clinical management issues, including case reports and case series demonstrating novel or interesting findings. This is of particular value in a field where clinicians are often faced with relatively rare conditions or clinical problems where the only supportive literature is at case report level. It is aimed at all specialists and trainees working in clinical infection-related disciplines including Clinical Microbiologists/Virologists, Infectious Diseases and Tropical Disease physicians, Public Health Specialists and supporting professional staff. The Journal publishes high-quality peer-reviewed clinically relevant research and case-based reports. Its aims are as follows: To publish high quality clinical research, of direct relevance to practising infection specialists, with an international scope. To publish state of the art reviews of areas of current clinical and research interest. To publish novel case reports of high educational value with relevant learning points. To publish educational and relevant clinical audit and quality improvement projects. To facilitate clinical decision making by publishing clinic-pathological conferences, illustrative case histories (with questions and learning points), and clinical images of high educational value and relevance. To facilitate problem-based learning and help trainees prepare for professional examinations including FRCPath (CICE) and international equivalent assessments.