The Computer Methods and Programs in Biomedicine-Update is an international open access peer-reviewed journal covering a broad spectrum of topics within biomedical research and medical practice. The articles explore the revolutionary advances in the application of computer-based medical solutions or proposed methodology applied to the fields of clinical research, translational medicine, informatics, imaging, data-driven care, medical devices, consumer health, nursing and public health. The journal intends to disseminate open access papers of the highest quality and is committed to ensuring a thorough, fair, and rapid review. CMPB Update welcomes articles that promote digital technologies, describe innovative computing methodologies and software systems research that help advance biomedical science, and improve medical care just like its partner journal Computer Methods and Programs in Biomedicine. The types of articles considered for publication include Original Research, Systematic Reviews and or Meta-analysis, Methodology, Research Letters, Viewpoint, Correspondence (in response to a paper published within three months) and editorials. Proposals for special focus issues from leading research groups will also be considered.