Evidence-Based Toxicology is a gold open-access journal created to support open science practices and the use of evidence-based methods in the toxicological and environmental health sciences. It is the official journal of the Evidence-Based Toxicology Collaboration.Primary research: Experimental and observational studies that apply the principles of evidence-based toxicology ( described here) when investigating potential human health impacts of environmental exposures.Secondary research: Systematic reviews, systematic evidence maps, and other studies that systematically summarise and synthesise evidence.Research into methods: Research of any appropriate design that aims to investigate or improve the utility, credibility, and/or transparency of primary or secondary research. This includes guidance, appraisal instruments, meta-epidemiological studies, etc.Research into the science-policy interface: Research of any appropriate design that aims to investigate and improve how scientific research informs decision-making, covering issues from risk assessment and risk management to equity and ethics.Protocols: The planned methods for any study design, primary or secondary, for any of the above types of research.Expert commentary: Advice, guidance, and comment designed to inform and educate readers about evolving contexts, trends, and practices in evidence-based toxicology.