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爱尔兰
投稿预审
Toxicology Letters 中科院3区 JCR:Q2 SCIE CA PubMed JST
发文量 33,261
被引量 418,091
影响因子(2025版) 2.749

An international journal for the rapid publication of novel reports on a range of aspects of toxicology, especially mechanisms of toxicity. Toxicology Letters serves as a multidisciplinary forum for research in toxicology. The prime aim is the rapid publication of research studies that are both novel and advance our understanding of a particular area. In addition to hypothesis-driven studies on mechanisms of mammalian toxicity, Toxicology Letters welcomes seminal work in the following areas: In silico toxicology Toxicokinetics Physiologically-based pharmacokinetic (PBPK) modeling Systems toxicology Predictive toxicology 3R research in toxicology New approach methodology (NAMs) Adverse outcome pathways (AOPs) Integrated testing strategies Systematic and narrative reviews and mini-reviews in various areas of toxicology will be published. Clinical, occupational and safety evaluation, hazard and risk assessment, regulatory toxicology, impact on man, animal and environment studies of sufficient novelty to warrant rapid publication will be considered. Toxicology Letters also publishes editorials, commentaries and contemporary issues in toxicology. The following types of work are not within the scopes of Toxicology Letters: Ecotoxicology studies Case studies Chemoprevention studies Pharmacological investigations Authors are advised to follow the ARRIVE guidelines (Animal Research: Reporting of In Vivo Experiments; https://arriveguidelines.org/) and the OECD guidance document on Good In Vitro Method Practices (GIVIMP; https://www.oecd.org/env/guidance-document-on-good-in-vitro-method-practices-givimp-9789264304796-en.htm). In vitro or in vivo investigations conducted at concentrations or doses of no relevance to human or animal exposure will not be considered. Routes of exposure other than those relevant to human or animal exposure need to be justified. Assessment of dose-response should be an integral component of any toxicological research report. Unless adequately justified, studies conducted at a single dose level may not be considered. Test materials must be chemically defined and characterized. Investigations of chemically undefined plant extracts or uncharacterized nanoparticles will not be considered.

  • 主办单位： ELSEVIER IRELAND LTD
  • 出版地区： CLARE
  • 出版周期： 半月刊
  • 别名： TOXICOL LETT;Toxicol Lett;Toxicol. Lett.;TOXICOLOGY LETTERS;Toxicology letters;毒理学快报
  • 国际标准连续出版物号/电子版： ISSN 0378-4274 / EISSN 1879-3169
  • 创刊时间： 1977年
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